Today, many friendly Spyware, Web Search, Toolbars, Advertisement Popup and Popup Blocker can be removed simply using the Microsoft MSConfig.exe program, which must run from the Run Window. To click the Start Button, then select Run... item.

The Run Window will appear, then type msconfig into Open: textbox and click OK button. Select the Startup Tab, all the startup programs will appear.

All the programs allowing automatically run when the computer starts are checked in the System Configuration Utility window. Basically, you can unchecked all of the programs and your computer will still works.
We suggest that you just keep the Anti-virus program checked and unchecked all others. So you will have more memory for running applications and your computer can run faster.
Certainly, you can keep all the programs you need for you work. If you don't know the program is a spyware or not, then you can type the program name into Google Search Box to search the articles. You will find the answer most of cases.